康复新液治疗小儿手足口病的临床疗效

2022.08.23

万光平余娟

【摘要】目的分析康复新液治疗小儿手足口病的临床疗效。方法 120例手足口病患儿，通过数字随机法分成对照组与实验组，各60例。对照组选择常规综合治疗，实验组在常规综合治疗的同时应用康复新液治疗。比较两组患儿的临床疗效、体征消失时间、不良反应发生情况。结果实验组的临床治疗总有效率为90.0%，高于对照组的70.0%，差异具有统计学意义（P<0.05）。实验组患儿的的口腔溃疡愈合、手足皮疹消退、退热时间分别为（3.34±0.91）、（3.17±1.04）、（1.47±0.41）d，均短于对照组的（5.14±1.32）、（4.95±1.22）、（2.87±0.76）d，差異均具有统计学意义（P<0.05）。治疗过程中，两组患儿均没有发生较为明显的不良反应。结论选择康复新液对手足口病患儿进行治疗能取得较为理想的临床疗效，不但能缩短患儿的病程，而且具有较高的安全性。

【关键词】康复新液;小儿手足口病;临床疗效

DOI：10.14163/j.cnki.11-5547/r.2020.02.047

Clinical efficacy of Kangfuxin liquid in the treatment of hand-foot-mouth disease in children? ?WAN Guang-ping， YU Juan. Department of Pediatrics， Meishan Peoples Hospital， Meishan 620010， China

【Abstract】 Objective? ?To analyze the clinical efficacy of Kangfuxin liquid in the treatment of hand-foot-mouth disease in children. Methods? ?A total of 120 children with hand-foot-mouth disease were divided into control group and experimental group by random number table method， with 60 cases in each group. The control group received conventional comprehensive therapy， and the experimental group received Kangfuxin liquid on the basis of conventional comprehensive therapy. The clinical efficacy， sign disappearance time and occurrence of adverse reactions was compared between the two groups. Results? ?The total effective rate of clinical treatment was 90.0%， which was higher than 70.0% in the control group， and the difference was statistically significant （P<0.05）. The healing time of oral ulcer， regression time of hand-foot rash and body temperature recovery time was （3.34±0.91），（3.17±1.04） and （1.47±0.41） d in the experimental group， which was shorter than （5.14±1.32），（4.95±1.22） and （2.87±0.76） d in the control group， and their difference was statistically significant （P<0.05）. During the treatment， no obvious adverse reactions occurred in both groups. Conclusion? ?Kangfuxin liquid shows ideal clinical efficacy for children with hand-foot-mouth disease， and it can not only shorten the course of disease， but also has high safety.

【Key words】 Kangfuxin liquid; Hand-foot-mouth disease in children; Clinical efficacy

手足口病是因为肠道病毒所引起的一种急性传染病，而年龄<5岁的儿童则是手足口病的主要发病人群[1]。手足口病患儿的临床症状主要表现为口腔、足、手等部位存在溃疡、皮疹等;部分患儿可能出现循环障碍、无菌性脑膜脑炎、心肌炎等并发症，如果患儿病情严重，则会对其生命安全造成威胁[2]。手足口病作为一种自限性疾病，现阶段临床中还缺乏治疗的特效方法，临床治疗主要为对症处理。本院在对手足口病患儿进行治疗时，采用康复新液治疗取得了较为理想的效果，现做如下分析。

1 资料与方法

1. 1 一般资料本文所选120例手足口病患儿均为本院2018年1月～2019年3月所收治，患儿家属签署知情同意书，本次研究经本院伦理协会研究批准同意[3]。通过数字随机法将患儿分成对照组与实验组，各60例。对照组中，男34例、女26例;病程18～56 h，平均病程（33.4±7.6）h;年龄1～11岁，?平均年龄（5.2±2.0）岁。实验组中，男37例、女23例;病程20～58 h，平均病程（33.1±8.4）h;年龄1～9岁，平均年龄（5.6±1.6）岁。两组患儿一般资料比较，差异无统计学意义（P>0.05），具有可比性。